Final fill for cell therapy
The cell therapy drug product is configured in different ways depending on the required delivery of the cells/tissues. For example, delivery of chondrocytes for cartilage repair is administered by an injection. Expanded cell doses are stored frozen and thawed for delivery via IV.
Finally, skin grafts are stored in packaging to ensure the integrity of individual sheets of cells. In most cases excipients used to prepare the cell dose are decided by the customer. Assurance of cell culture components removal is critical, especially if cytokines and animal sera are used.