Separations for Proteins and Large Biological Molecules

Large Molecule LC (Bio LC)

The separation of active ingredients that have been manufactured using biological processes often requires a different approach. 

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Hydrophobic Interaction Chromatography (HIC)

HIC is an excellent technique for the separation of proteins without causing denaturing, therefore scaleable from analytical to downstream processing

Size Exclusion Chromatography (SEC)

SEC is used to separate components according to their molecular size. It is non-adsorbtive meaning no chemical interaction.

Ion Exchange Columns

Ion exchange separates on the basis of charge on the molecule. It is used often for the separation of peptides, proteins and oligonucleotides

Widepore Reversed Phase HPLC

A 300Å pore size with a C4 or C8 phase is suitable for small proteins and large peptides.  Proteins are retained by adsorbtion of the hydrophobic foot

Chromatography process media

You are looking for a range of media manufactured under cGMP conditions that can fulfill your needs from lab to production scale.

Automation Protein Purification

If you need to improve efficiency in your laboratory protein purification, instrumentation and software could help you acheive your goal.