Collagen II is the principal collagenous component of cartilage, intervertebral disc, and vitreous humour. Collagen II supports chondrocyte adhesion and may influence the differentiated phenotype of these cells. In culture, collagen II is used for attachment and differentiation of chondrocytes. It can also be used as an in vivo model in rats and mice for arthritis studies (injection of bovine collagen II induces arthritis).
Quality controlled by SDS-PAGE and tested and found negative for bacteria, fungi, and mycoplasma