Vincristine sulphate ≥98%
Supplier: Enzo Life Sciences
Microtubule inhibitor
Plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Depolymerizes microtubules and blocks binding of tubulin to microtubule proteins. Causes aberrant tubulin polymerization. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent. Posttranscriptionally downregulates HIF-1α expression.
Formula:
C₄₆H₅₈N₄O₁₄S MW: 923,04 g/mol |
CAS Number:
2068-78-2 |
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