Human recombinant CEACAM5 (from cells)Supplier: ProSci
PRSI92-685EA 515 EURPRSI92-685
Human recombinant CEACAM5 (from cells)
Proteins and Peptides
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterised by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumour cells from apoptosis. It is commonly used as a cancer marker.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.