Anti-CYCS Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences
ALEXADI-AAM-175-EEA 467 EUR
ALEXADI-AAM-175-E
Anti-CYCS Mouse Monoclonal Antibody
Antibodies
Cytochrome c is an electron transport protein from mitochondria.  A primary means of caspase activation by p53 is through induction of cytochrome c release from mitochondria.  Cleavage of Bid, a Bcl 2 family member, by caspase-8 produces a truncated tBid molecule which triggers mitochondria release of cytochrome c which binds to the adaptor protein Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex.  This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death.

  • For Immunohistochemistry, Western Blot

Recognizes human, mouse, rat, bovine, guinea pig, hamster, monkey, rabbit and sheep Cytochrome c. Detects a band of ~14kDa by Western blot.

Type: Primary
Antigen: CYCS
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype:
Reactivity:
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