Anti-AMSH Rabbit Polyclonal Antibody

Supplier: Axxora
ALEXBMLPW06550025EA 98 EUR
ALEXBMLPW06550025 ALEXBMLPW06550100
Anti-AMSH Rabbit Polyclonal Antibody
Antibodies
The JAMM domain containing zinc metalloprotease AMSH (Associated Molecule with the SH3-domain of STAM) acts as a deubiquitinylating enzyme during the sorting process to regulate receptor trafficking by specifically cleaving Lys63-linked polyubiquitin chains from internalized receptors. The amino-terminal half of AMSH proteins interacts with clathrin and ESCRT proteins on the endosome, whereas the C-terminal half is engaged in Lys63-linkage-specific deubiquitination. AMSH mediated cleavage of K63-linked ubiquitin chains is enhanced in the presence of its binding partner STAM.

  • For Western Blot

Recognizes human AMSH.

Type: Primary
Antigen: AMSH
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human
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