Anti-STIM1 Polyclonal Antibody

Supplier: Axxora
ALEXBML-SA676-0200EA 663 EUR
ALEXBML-SA676-0200
Anti-STIM1 Polyclonal Antibody
Antibodies
Cytosolic calcium (Ca2+) has long been known to act as a key second messenger in many intracellular pathways including synaptic transmission, muscle contraction, hormonal secretion, cell growth and proliferation. The mechanism controlling intracellular Ca2+ level influx either by the calcium-release-activated Ca2+ channels (CRAC), or from intracellular stores, has become of great interest to researchers. Several key players of the store operated complex have been identified; the Orai family consisting of three members, Orai1-3, and the STIM family, which consists of two members, STIM1 and STIM2. Orai1 (also known as CRACM1) acts as the store-operated calcium channel (SOC) and STIM1 as the endoplasmic reticulum Ca2+ sensor3,4. The majority of STIM1 appears to be localized intracellularly at the ER membrane while low expression of STIM1 has been detected on the cell surface of several cell types.

  • For Immunocytochemistry, Immunohistochemistry, Western Blot

Recognizes human and rat STIM1.

Reconstitute with 50μl or 200μl distilled water. Further dilutions should be made with medium containing a carrier protein such as 1% BSA.

Type: Primary
Antigen: STIM1
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host:
Isotype:
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR