Anti-Matriptase Mouse Monoclonal Antibody [clone: D11]

Supplier: Axxora
ALEXADI90510080100EA 639 EUR
Anti-Matriptase Mouse Monoclonal Antibody [clone: D11]
The protein encoded by the Matriptase gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion and metastasis.

Type: Primary
Antigen: Matriptase
Clonality: Monoclonal
Clone: D11
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG
Reactivity: Human
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