SEW-2871 ≥98%
Supplier: Enzo Life Sciences
Synonyms:
5-(4-Phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole
, 5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole
SEW-2871 is a novel, potent EDG receptor agonist structurally unrelated to sphingosine-1-phosphate and is highly selective for the human S1P1 receptor. It inhibits lymphocyte recirculation in vivo and produces immunosuppression without associated bradycardia which is induced by other less selective S1P agonists. In mice SEW-2871 blocked TNFα induced monocyte adhesion to endothelium.
- S1P receptor ligand
White solid.
Formula:
C₂₀H₁₀F₆N₂OS MW: 440,4 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00096600 CAS Number: 256414-75-2 |
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