Lipopolysaccharides (from E.coli) serotype J5 (Rc), TLRgrade™ ready-to-use

Supplier: Enzo Life Sciences

ALEXALX581014L002EA 299 EUR
Lipopolysaccharides (from E.coli) serotype J5 (Rc), TLRgrade™ ready-to-use

TLR4 activator.

Rough (R)-form LPS isolated and purified from E. coli J5 (Rc mutant) by a modification of the PCP extraction method, converted to the uniform sodium salt form and dissolved in sterile pyrogen-free double distilled water.

Strong activator of Toll-like receptor 4 (TLR4). Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. No further re-extraction required. Smooth (S)-form LPS are commonly the preferred choice for whole animal studies, whereas Rough (R)-form LPS are primarily used in cellular in vitro activation studies.

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Specification Test Results

Concentration 1 mg/ml
Formulation Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water
Purity Absence of detectable protein or DNA contaminants with agonistic TLR activity

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