Rabbit Extendin-4 Acetate

Supplier: Cayman Chemical
CAYM11096-5EA 893 EUR
CAYM11096-5 CAYM11096-500 CAYM11096-1
Rabbit Extendin-4 Acetate
Proteins and Peptides
Exendin-4 is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor (Ki = 136 pM).

By activating the GLP-1 receptor, it stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells, supporting efficacy in type 2 diabetes.

Exendin-4 was first isolated from the venom of H. horridum and consequently synthesised, with the recombinant peptide referred to as exenatide. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neuropathies associated with type 2 diabetes and in neurodegenerative diseases. Exenatide also has anxiolytic and anti-depressant effects and induces satiety.

Caution: These products are not for human or veterinary use.
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